New leukemia treatment exceeds 'wildest expectations'
A single shot could be one of the biggest advances in cancer research in decades, scientists say.
By Robert Bazell Chief science and health correspondent NBC News
Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades.
In the research published Wednesday, doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone.
The results of the preliminary test “exceeded our wildest expectations,” says immunologist Dr. Carl June, a member of the Abramson Cancer Center's research team.
Dr. Edgar Engleman, a cancer immunologist at Stanford University School of Medicine who was not involved in the research calls the results“remarkable ... great stuff.”
The Penn scientists targeted chroniclymphocytic leukemia (CLL), the most common type of the blood disease. It strikes some 15,000 people in the United States, mostly adults, and kills 4,300 every year. Chemotherapy and radiation can hold this form of leukemia at bay for years, but until now the only cure has been a bone marrow transplant. A bone marrow transplant requires a suitable match, works only about half the time, and often brings on severe, life-threatening side effects such as pain and infection.
Disponível em: <http://www.theglobeandmail.com/life/health/new-health/health-news/experimental-cancer-therapy-wipes-out-leukemiastudy/article2125709/>. Acesso em: 13 set. 2011. [Excerto].
hold at bay: neutralizar, manter a distância
bone marrow: medula óssea
The new leukemia treatment
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